Your points, along with your other important attributes, are saved when you quit (in the 'persona file', if you're interested!). What isn't saved is a note of your location when you quit, what you were carrying, nor any abilities/disabilities you had which resulted from magic used on you. For example, if someone had cast a 'glow' spell at you so you could see in the dark, this would not be recorded when you quit (however, neither would the results of a 'deafen' or similar spell!).
What happens to my points when I quit?